Do Statins Weaken Muscles?

Do statins weaken muscles? Statins are commonly prescribed and successful lipid-lowering medications that reduce the risks associated with cardiovascular disease. The side effects most commonly associated with statin use involve muscle cramping, soreness, fatigue, weakness, and, in rare cases, rapid muscle breakdown that can lead to death.

One may also ask, Why do statins cause muscle breakdown?

Statin medications and low cholesterol levels can both contribute to low CoQ10 levels. Calcium leakage. Calcium helps muscles contract, but when calcium leaks from muscle cells unintentionally, it can damage your muscle cells which causes muscle pain.

At same time, Can muscle damage from statins be reversed? The damage is typically reversible once the person stops taking the statin. More rarely still, a severe type of muscle damage called rhabdomyolysis may occur, in an estimated 2–3 in 100,000 people taking this type of drug per year.

Secondly, How do statins affect muscle growth?

Muscle pain and cramps are common side effects of statins. As an MDC and Charité research group now reports in Scientific Reports, the cholesterol reducers actually influence thousands of genes in muscle cells – thereby hindering cell growth and division. Around 20 million people worldwide take statins.

Do statins cause weak legs?

However, for around 25% of patients, statins can give rise to unpleasant side effects in the form of muscle weakness, pain and cramps, without any sign of damage to the tissue. These side effects can impair quality of life and often cause patients to stop taking the drugs.

Related Question for Do Statins Weaken Muscles?

Which muscles are most affected by statins?

Within a month of starting statin therapy, they may feel aches or weakness in the large muscles of their arms, shoulders, thighs or buttocks on both sides of the body. About 5 to 10% of people who try statins are affected. It's more common in the elderly, in women and in those taking the more potent statins.

How do you know if you have muscle damage from statins?

Rhabdomyolysis or milder forms of muscle inflammation from statins can be diagnosed with a blood test measuring levels of the enzyme creatinine kinase. If you notice moderate or severe muscle aches after starting to take a statin, contact your doctor.

What can be taken instead of statins?

7 cholesterol-lowering alternatives to statins

  • Fibrates. Mostly used for lowering triglyceride levels in patients whose levels are very high and could cause pancreatitis.
  • Plant stanols and sterols.
  • Cholestyramine and other bile acid-binding resins.
  • Niacin.
  • Policosanol.
  • Red yeast rice extract (RYRE)
  • Natural products.

  • Do statins clear the arteries of plaque?

    Statins help lower low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, in the blood. They draw cholesterol out of plaque and stabilize plaque, Blaha says.

    Do statins make you age faster?

    Statins do have side effects, all medication does to some extent. And some of those side effects reported could also be deemed to be signs of premature aging. Memory loss and weakness or fatigue are both listed under 'uncommon side effects' on the NHS website.

    Do statins cause more harm than good?

    NHS recommendations state millions of people who have not suffered a heart attack or stroke should take statins as a preventative measure. However, experts writing in the British Medical Journal (BMJ) said the drugs could do more harm than good, and offer a tiny benefit for those people at low risk.

    Do statins make it harder to exercise?

    Taking cholesterol-lowering statin drugs seemed to make exercise more difficult and less beneficial, a new study in mice suggests.

    Do statins reduce athletic performance?

    Conclusion: Statins may increase the incidence of exercise-related muscle complaints and in some studies augment the exercise-induced rise in muscle enzymes, but statins do not consistently reduce muscle strength, endurance, overall exercise performance or physical activity.

    Do athletes take statins?

    Although statins increase exercise muscle injury and may reduce exercise training response, they appear to be safe in athletes, a presenter said. The evidence suggesting that statins may affect exercise performance were anecdotal or were from uncontrolled studies, Paul D.

    Can you build muscle while taking statins?

    Although high-dose statin therapy may increase the incidence of muscle complaints or cause slight rises in muscle enzymes, these drugs do not reduce muscle strength or endurance.

    What do statins do besides lower cholesterol?

    Statins offer other benefits besides lowering your cholesterol. For example, they help stabilize the blood vessel lining, which benefits the whole body. This also makes plaque less likely to rupture in the heart, lowering the risk of a heart attack.

    Do statins make arthritis worse?

    Study: “The only significant finding indicated that increased duration of statin use was associated with worsening in knee pain and osteoarthritis.” There is no general consensus that statins help or statins make things worse.

    Do statins make you gain weight?

    As with many medications, statins may cause side effects, including digestive problems, muscle pain and weakness, and cognitive dysfunction. Another side effect that's been linked to statins is weight gain.

    How does the body get rid of statins?

    Ramp up your lifestyle changes.

    Commit to an exercise routine, lose weight if you need to, and adopt a heart- healthy eating plan such as the Mediterranean diet. Doing so may enable you to reduce your statin dosage, or possibly even lower your cholesterol enough to enable you to stop the statin.

    At what age should you stop statins?

    Statins are drugs that lower your cholesterol. But if you are age 75 or older and you haven't had symptoms of heart disease, statins may be a bad idea. Here's why: Adults age 75 and older may not need statins.

    Can you get permanent muscle damage from statins?

    Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.

    Can muscle pain from statins be permanent?

    Patients experiencing muscle pain and weakness as a result of statin treatment may continue to suffer symptoms long after stopping the drugs, French researchers reported.

    Which statin has least side effects?

    In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.

    Can I take my statin every other day?

    5. The cholesterol-lowering action of alternate-day statins is as effective as daily dosing in many individuals. 6. To maintain the same degree of decrease in LDL-C when giving the statins on alternate days, the dose of the statins frequently needs to be increased.

    Do I really need a statin?

    If your risk is very low, you probably won't need a statin, unless your LDL is above 190 mg/dL (4.92 mmol/L). If your risk is very high — for example, you've had a heart attack in the past — a statin may be helpful even if you don't have high cholesterol.

    Does turmeric help cholesterol?

    From these studies, it appears that turmeric mainly affects total cholesterol, LDL cholesterol, and triglyceride levels. One study conducted in rabbits fed a high-fat diet showed that turmeric appeared to lower LDL cholesterol levels and triglycerides, as well as preventing LDL from being oxidized.

    Is it OK to take a break from statins?

    It's possible for some people to stop taking statins safely, but it can be especially risky for others. For instance, if you have a history of heart attack or stroke, it's not recommended that you stop taking these drugs. This is because you're more likely to have another such problem when you discontinue statins.

    What foods should be avoided when taking statins?

    While taking atorvastatin (Lipitor), avoid high-fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.

    Do statins shorten your life?

    “The study showed that taking statins for 6 years reduced death from cardiovascular disease by 24 percent, and overall mortality by 23 percent.”

    Why do statins have to be taken at night?

    They act by inhibiting the enzyme HMG CoA reductase, which controls synthesis of cholesterol in the liver. Most manufacturers of statins recommend that they are taken at night, on the basis of physiological studies which show that most cholesterol is synthesised when dietary intake is at its lowest.

    How do you replace statins naturally?

  • Foods high in soluble fiber and plant phytosterols, such as legumes, avocados, broccoli and other fruits and vegetables.
  • Whole grains, including oatmeal, quinoa and barley.

  • What is the real truth about statins?

    The truth: Taking a statin can increase blood sugar levels. If you're already pre-diabetic, that slight hike in blood sugar could push you into diabetes. Even so, research suggests that this risk of diabetes caused by statins is about 0.5-1%. So in that sense, the benefits of statin therapy greatly outweigh the risks.

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